Mordant

He was good company, with a mordant sense of humour and a strong sense of duty. 
Unfortunately, his brain was starved of oxygen and he was left brain damaged, with spastic paraplegia. 
His insouciance and could-not-care-less attitude is becoming intolerable. 
The law proscribes driving a car while intoxicated. 
Various scratches and cuts line her arms and face; a pus-filled abscess burns on her right arm. 

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